{"id":5231,"date":"2026-04-13T12:43:13","date_gmt":"2026-04-13T10:43:13","guid":{"rendered":"https:\/\/splaboratorija.rs\/?p=5231"},"modified":"2026-04-14T08:09:45","modified_gmt":"2026-04-14T06:09:45","slug":"content-of-active-substances-in-dietary-supplements","status":"publish","type":"post","link":"https:\/\/splaboratorija.rs\/en\/2026\/04\/13\/content-of-active-substances-in-dietary-supplements\/","title":{"rendered":"Content of active ingredients in dietary supplements"},"content":{"rendered":"\n
In the competitive market for dietary supplements, ensuring product quality and safety is crucial.<\/p>\n\n\n
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Significance of confirmation<\/strong><\/h2>\n\n\n\n
The dietary supplement industry faces increasing scrutiny regarding the accuracy of product claims and the actual content of active ingredients. Independent checks and laboratory tests can confirm that the products meet the stated claims and comply with national and international regulations. Regular testing protects consumer health and improves brand credibility in the dietary supplement market.<\/p>\n\n\n\n
Understanding the dietary supplement declaration<\/strong><\/h2>\n\n\n\n
The dietary supplement declaration serves as the primary source of information for consumers. According to the Regulation on dietary supplements (dietary supplements) (“Official Gazette of RS”, no. 45\/2022, 20\/2023 and 73\/2024 \u2013 other reg.), in addition to the requirements of the regulations governing the declaration, labeling and advertising of food, the declaration of dietary supplements must contain:<\/p>\n\n\n\n
1) names of categories of nutrients or substances that characterize the product or description of the nature of nutrients or substances;<\/p>\n\n\n\n
2) the amount of product recommended for daily intake;<\/p>\n\n\n\n
3) a warning that the recommended daily dose must not be exceeded;<\/p>\n\n\n\n
4) note that nutritional supplements cannot be used as a substitute for a varied diet;<\/p>\n\n\n\n
5) note that the products should be kept out of the reach of small children;<\/p>\n\n\n\n
6) instructions on how to apply the nutritional supplement; application restrictions and special warnings for potentially risky categories: children, pregnant women, nursing mothers, people suffering from chronic diseases, etc.<\/p>\n\n\n\n
The declaration may contain information about the purpose of the product where applicable without misleading the consumer.<\/p>\n\n\n\n
The veracity of the supplement declaration can also be confirmed by product analysis, protecting consumers from misleading or false claims and ensuring their safety.<\/p>\n\n\n\n
The role of active ingredients in product effectiveness<\/strong><\/h2>\n\n\n\n
Active ingredients determine the effectiveness of dietary supplements containing certain compounds. Whether it is minerals, vitamins or plant extracts, their presence and effect must be in accordance with the manufacturer’s declaration. Test methods such as mass spectrometry are key to the precise quantification of these biologically active components, ensuring that the claimed benefits of the supplement are substantiated and that the product provides the desired therapeutic effect.<\/p>\n\n\n\n
Compliance with regulations<\/strong><\/h2>\n\n\n\n
Regulatory compliance is essential for nutritional supplement manufacturers. The regulations cover various aspects, including good manufacturing practice (GMP), accurate labeling and the absence of contaminants. Adherence to these standards not only ensures market access, but also builds consumer confidence in the safety and quality of nutritional supplements.<\/p>\n\n\n\n
Regulations and standards related to products of the usual composition in terms of general and nutritional declaration and labeling, measurements and limits of deviation from the declared quantity of packaged foods, quality, conditions of use of additives, aromas, enzyme preparations and auxiliaries, requirements for microbiological safety and maximum permitted amounts of contaminants and residues, are also applied to nutritional supplements, if the Regulation on nutritional supplements (dietetic supplements) (“Official Gazette of RS”, no. 45\/2022, 20\/2023 and 73\/2024 \u2013 other reg.) is not prescribed otherwise.<\/strong><\/p>\n\n\n\n
Analytical techniques<\/strong><\/h2>\n\n\n\n
Mass spectrometry<\/strong> is a key analytical technique in the verification of substances in dietary supplements. This sophisticated method allows precise identification and quantification of active ingredients, ensuring that dietary supplements containing these compounds meet the manufacturer’s declaration. By using mass spectrometry, laboratories can detect even traces of biologically active components, thus confirming the quality of dietary supplements and strengthening consumer confidence.<\/p>\n\n\n\n
Analysis of the elemental composition<\/strong> of dietary supplements is crucial for the detection of heavy metals and other contaminants. Advanced methods, such as inductively coupled plasma with mass spectrometry (ICP-MS) offer high sensitivity and accuracy in determining the presence and concentration of various elements.<\/p>\n\n\n\n
High performance liquid chromatography (HPLC)<\/strong> is widely used in the confirmation of active compounds in dietary supplements. This technique separates, identifies and quantifies each component, ensuring the effectiveness and purity of the supplement. HPLC is particularly effective for the analysis of vitamins and other active ingredients, thereby supporting the accuracy of the dietary supplement label and confirming compliance with good manufacturing practices.<\/p>\n\n\n
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Benefits of accurate testing for manufacturers<\/strong><\/h2>\n\n\n\n
\u2022 Establishing credibility through accurate declarations <\/strong>– confirmation of active ingredients is essential to establishing credibility in the dietary supplement market. When manufacturers can prove that their product’s label accurately reflects the content of active compounds, they build trust with consumers. This transparency not only improves brand reputation, but also provides a competitive advantage, as consumers increasingly demand detailed information and proof of product quality and safety of dietary supplements.<\/p>\n\n\n\n
\u2022 Maintaining product stability and safety<\/strong> – testing ensures that nutritional supplements maintain their stability and safety throughout their shelf life. Regular analysis helps detect any degradation of active ingredients. By following good manufacturing practices and conducting thorough checks, manufacturers can ensure that their products remain effective and safe for consumption.<\/p>\n\n\n
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Laboratory services in support of production<\/strong><\/h2>\n\n\n\n
Precise confirmation of active ingredients, regular checks and adherence to good manufacturing practices are key elements in the production of dietary supplements. Manufacturers who prioritize these measures can establish credibility, maintain product stability and gain a competitive advantage in the dynamic dietary supplement market.<\/p>\n\n\n\n
To ensure the highest standards of nutritional supplement quality and compliance, our accredited laboratory offers comprehensive testing services, from individual vitamin analysis to complete mineral profiles, ensuring accurate verification of active ingredient content and compliance with regulatory requirements. Whether you need to verify elemental composition or confirm the presence of active compounds, our experts are at your disposal to provide information and support to meet all your testing needs.<\/p>\n\n\n\n
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